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2025
Announcing the NIH Autism Data Science Initiative Research Opportunity
Today, NIH released a Research Opportunity Announcement for the Autism Data Science Initiative (ADSI). We are spotlighting this other transaction here as it is a high priority for leadership within NIH and the U.S. Department of Health and Human Services. It also encompasses several efforts of general interest for NIH supported research including supporting data resources, participant privacy, and research replicability/validation.
Why Did NIH Expire Some Funding Opportunities Because of the Simplified Review Framework, and What Does It Mean for My Application?
The simplified review framework went into effect earlier in 2025, and NIH has been busy preparing staff, peer reviewers, and study section chairs for its arrival at summer 2025 review meetings. To avoid confusion and reduce reviewer burden at review meetings, NIH has expired identified NOFOs that were not expired or reissued as indicated in the implementation plan shared in early 2024.
If You See Something Amiss, Say Something
If you ever come across misconduct, whether it be harassment, fraud, grant scams, research misconduct, peer review violations, or foreign interference, please report it.
Protecting Human Genomic Data When Developing Generative Artificial Intelligence Tools and Applications
NIH issued a Guide notice (NOT-OD-25-081) clarifying how to protect human genomic data obtained from NIH controlled-access repositories when using and developing generative artificial intelligence models consistent with the Genomic Data Sharing Policy.
Automatic Extension of Early Stage Investigator Status to Address Recent Delays
NIH has granted the automatic extension of Early Stage Investigator (ESI) eligibility. This extension addresses delays impacting grant application submissions, peer review, or award processing timelines between January 1, 2025, and May 31, 2025.
Reminder About Inclusion of Participants in Clinical Research
NIH continues to follow all laws (e.g., 42 USC 289a-2) and existing NIH policies that help NIH ensure clinical research includes the appropriate participant demographics to make certain the scientific question under study is addressed in a robust and generalizable manner.
How Are Childcare Costs Issued to Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Awards?
NIH has recently revised the process by which NRSA childcare funds are distributed to institutional research training awards.
New NIH Foreign Subaward Structure Enhances Integrity, Accountability, Oversight, and National Security of NIH Funded Research
Effective with the next NIH award cycle, all NIH-funded research involving foreign subawards must be structured as subprojects directly linked to the prime award. Foreign subawards are prohibited from being nested under the parent grant.
Accelerating Implementation of the NIH 2024 Public Access Policy
NIH has announced that the 2024 NIH Public Access Policy will now go into effect on July 1, 2025.
Certificate of Confidentiality (CoC) System is Temporarily Unavailable
NIH is currently undergoing a renewal of the Paperwork Reduction Act (PRA) approval for the NIH Certificate of Confidentiality (CoC) system. NIH will not be accepting requests to the CoC system or Institutional Official verifications for non-NIH funded research during this time.
Reminder: Application Requirements for Projects Involving Activities Outside of the United States or Partnerships with International Collaborators
NIH would like to remind the extramural research community about long-standing application requirements for projects involving activities outside of the United States or partnerships with international collaborators.
New Home for Extramural Nexus on the NIH Grants and Funding Website
Your source for NIH grants news has moved to the NIH Grants and Funding website, creating a one-stop shop for your journey through the grants process! The Extramural Nexus news content is now next to the policy and process resources you need.
Implementation of New Initiatives and Policies Page Now Available
We have posted an Implementation of New Initiatives and Policies page on the public NIH Grants & Funding Website to pull together the latest information on recent and upcoming changes that impact applications and grants administration.
How Can You Effectively Prepare NIH Research Project Grant Applications for Due Dates in 2025 and Beyond?
The framework is a new way of reviewing the same research strategies you’ve always developed, which means neither the components nor the structure of your application are expected to change.
Find NIH Funding Information More Quickly and Easily with RCDC’s New Look and Feel
The new look and feel of the NIH Research, Condition, and Disease Categorization (RCDC) Categorical Spending webpage adds to NIH’s long-standing efforts to enhance transparency and accountability into funding decisions.
Reviewer Guidance for the Simplified Review Framework
Do you want to learn more about how applications will be reviewed under the simplified review framework for most research project grants? Learn more whether you’re a peer reviewer awaiting training or a researcher preparing an application.
Explore a Typical NIH Funding Opportunity
The first step to NIH funding is closely reading your funding opportunity, which contains important information about eligibility, application submission, and review.
Away For a Bit? Delegate Your Tasks in eRA Commons
Are you a signing official or principal investigator planning to be away from the office? Do not let award management tasks pile up in your absence. Simply use the delegation feature in eRA Commons to allow others to act on your behalf.
To Do in 2025: Keep Your eRA Personal Profile Updated
The Personal Profile module in eRA Commons is where you — as a PI, award recipient, trainee, reviewer or other user — tell NIH and other awarding agencies about yourself. Keep it up to date so awarding agencies can process your award!
Information for…You! Curated Resources by Role
If you’re not sure where to start looking for the grants process information you need, start with our Information For pages, designed with each role in mind!
How Does NIH Determine Early Stage Investigator Eligibility?
Early Stage Investigator eligibility is calculated in the eRA Commons system, using information provided by the investigator in their eRA Commons Personal Profile. Learn more about how eligibility is determined on the ESI status page.
What Should a Researcher Know If Their Animal Study May Involve Another Institution?
The short answer: collaborations can offer significant benefits for scientific discovery. However, there are a number of components to be considered prior to establishing a collaboration when research involves animal activity.